Now Foods Niacin 500 MG - 250 Tablets

I used the "NORMAL" Niacinamid 500mg and NO problem or so for a 30+ year old very healthy slim adult. When i did reorder they shipped the sustained release and without knowledge of that i took 1 pill and after 2 days i had extrem pain in the stomach region and dark pee for the next 14 days. At times i thought i have to go to emergency. After finding out the studies of "sustain-release" induced niacin causing hepatitis and liver toxicity i was kind of released that the cause of my terrible condition was external and therefore in future easy to control, at the same time disappointed that this huge negative side effect is not red printed at IHERB to avoid suffering. Also it seems NOW and IHERB promote this danagerous "sustain-release" more since the "normal" one does ... MoreI used the "NORMAL" Niacinamid 500mg and NO problem or so for a 30+ year old very healthy slim adult. When i did reorder they shipped the sustained release and without knowledge of that i took 1 pill and after 2 days i had extrem pain in the stomach region and dark pee for the next 14 days. At times i thought i have to go to emergency. After finding out the studies of "sustain-release" induced niacin causing hepatitis and liver toxicity i was kind of released that the cause of my terrible condition was external and therefore in future easy to control, at the same time disappointed that this huge negative side effect is not red printed at IHERB to avoid suffering. Also it seems NOW and IHERB promote this danagerous "sustain-release" more since the "normal" one does not even exists anymore above 100 capsules. What a shame. BE WARNED!!

If you are like me dealing with lyme disease and hyperactivity of NMDA receptors in the brain, then Niacin works fantastic. Niacin, as a precursor of NADH, helps to block the creation of quinolinic acid by a negative feedback loop in the kynurenine pathway. Quinolinic acid is a potent NMDA receptor stimulator and causes toxicity and hyperactivity in the brain. Lyme is potent inducer of quinolinic acid, and so Niacin helps to combat that. Niacin calms the overstimulated NMDA receptors down and helps to calm the nervous system. Works great in conjunction with P5P. magnesium threonate and L-theanine.This 500mg size is enough to make you flush. I dont experience flushing on every occasion. Flushing feels like your getting hot inside and your skin is burning from ... MoreIf you are like me dealing with lyme disease and hyperactivity of NMDA receptors in the brain, then Niacin works fantastic. Niacin, as a precursor of NADH, helps to block the creation of quinolinic acid by a negative feedback loop in the kynurenine pathway. Quinolinic acid is a potent NMDA receptor stimulator and causes toxicity and hyperactivity in the brain. Lyme is potent inducer of quinolinic acid, and so Niacin helps to combat that. Niacin calms the overstimulated NMDA receptors down and helps to calm the nervous system. Works great in conjunction with P5P. magnesium threonate and L-theanine.This 500mg size is enough to make you flush. I dont experience flushing on every occasion. Flushing feels like your getting hot inside and your skin is burning from stinging nettles or something. Not a nice reaction but still worth it for the benefits.

Niacin, a form of Vitamin B3 was recommended to me by a Natropath to help relieve calf muscle cramps and migraines. I was recently getting cluster headaches and/or migraines 2 - 3 times a week. Also waking up with calf muscle cramps in the night. I've been taking 1 pill a day for 10 days and neither condition has recurred. I also have less joint pain. It seems to be working for what I had it recommended for and I have no side effects other than the typical predicted flushing so I am happy with it.How it works: Niacin works as a vasodilator that temporarily expands the blood vessels through histamine release. Typically you may get a temporary flushing effect with this form of B3 (there a no flush forms). Around 15 minutes of taking I get around a minute of a bright ... MoreNiacin, a form of Vitamin B3 was recommended to me by a Natropath to help relieve calf muscle cramps and migraines. I was recently getting cluster headaches and/or migraines 2 - 3 times a week. Also waking up with calf muscle cramps in the night. I've been taking 1 pill a day for 10 days and neither condition has recurred. I also have less joint pain. It seems to be working for what I had it recommended for and I have no side effects other than the typical predicted flushing so I am happy with it.How it works: Niacin works as a vasodilator that temporarily expands the blood vessels through histamine release. Typically you may get a temporary flushing effect with this form of B3 (there a no flush forms). Around 15 minutes of taking I get around a minute of a bright pink hot feeling face and joints (knuckles, elbows, and knee caps) then its completely gone.CONDITIONS: In history, Niacin deficiency or "pellagra", was called the disease of the 4 D’s: diarrhoea, dermatitis, dementia/depression, and (eventually) death. The internet says Niacin deficiency may present as ulcer formation, dizziness, bad breath, headaches, nausea, irritability, nerves, depression and stress. Presumably if you are low then supplementation will restore levels and ease these conditions. I was hoping it would fix bad breath, low blood pressure, and my dermatitis as a bonus as they mentioned but it was a no for me lol. Must have another cause. But I'm not stressed about it, which is on the list, ha.WARNINGS: High doses should be avoided in: diabetes, low blood pressure, gout, liver disease or ulcers. I have two conditions on the list, low blood pressure and the gout that is firmly under control by eating very low carb and low oxalates, and I feel ok to take this Niacin. My Natropath says one pill is a low dose and B3 is water soluble so any excess goes down the toilet.