Buy wisely
Buy wiselyBuy wisely
For RetailersFor developers
  1. Home
  2. Health & Beauty
  3. Skincare
  4. Cleansers
  5. La Roche Posay Effaclar H Iso-Biome 40ml
Buy wisely

BuyWisely is your one stop price comparison platform, delivering the best deals from over 20,000 online shops. We empower shoppers to make smart, cost-effective choices by offering transparent pricing, price history, and the latest deals across a broad range of products. With BuyWisely, your money goes further.

Popular Shops
JB Hi-Fi
The Good Guys
Harvey Norman
Appliances Online
Bing Lee
Kogan
Amazon
Officeworks
Contact Us
[email protected]
Affiliate Disclosure
Legal Information
Privacy Policy
Logos provided by Logo.dev
© 2026 BuyWisely•Price data powered by pricesAPI.io•Retailers: SellWisely.io
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml
La Roche Posay Effaclar H Iso-Biome 40ml

La Roche Posay Effaclar H Iso-Biome 40ml

$23.37

(2,380 reviews)

Moisturizing cream formulated for oily, acne-prone skin that has undergone drying treatments. Restores intense hydration, reduces imperfections, and strengthens the skin barrier for lasting comfort.40 ml packaging. Facial moisturizing cream specifically designed for oily, acne-prone skin weakened by drying treatments. Its formula helps restore lost hydration, alleviating dryness and tightness. It incorporates niacinamide to repair the skin, Orellana extract that acts on excess sebum and hyperkeratinization, and Aqua Posae Filiformis, a key prebiotic to rebalance the skin microbiome. This complex helps reduce the appearance of blemishes, blackheads, and post-acne marks while strengthening the skin's protective function. Its cream texture provides long-lasting hydration without a greasy feel, making it easy to integrate into the daily facial care routine. Suitable for use on the face, especially for skin that experiences dryness after anti-acne treatments, it can be complemented with facial sun protection products and natural makeup for complete protection and a balanced finish. Its soothing and repairing action is compatible with other topical treatments, enhancing the effectiveness of cosmetics adapted for oily skin. Dermatologically tested, this cream helps maintain skin health and improve the overall appearance of imperfect skin through deep, hydrating, and restorative care.

Moisturizing cream formulated for oily, acne-prone skin that has undergone drying treatments. Restores intense hydration, reduces imperfections, and strengthens the skin barrier for lasting comfort.40 ml packaging. Facial moisturizing cream specifically designed for oily, acne-prone skin weakened by drying treatments. Its formula helps restore lost hydration, alleviating dryness and tightness. It incorporates niacinamide to repair the skin, Orellana extract that acts on excess sebum and hyperkeratinization, and Aqua Posae Filiformis, a key prebiotic to rebalance the skin microbiome. This complex helps reduce the appearance of blemishes, blackheads, and post-acne marks while strengthening the skin's protective function. Its cream texture provides long-lasting hydration without a greasy feel, making it easy to integrate into the daily facial care routine. Suitable for use on the face, especially for skin that experiences dryness after anti-acne treatments, it can be complemented with facial sun protection products and natural makeup for complete protection and a balanced finish. Its soothing and repairing action is compatible with other topical treatments, enhancing the effectiveness of cosmetics adapted for oily skin. Dermatologically tested, this cream helps maintain skin health and improve the overall appearance of imperfect skin through deep, hydrating, and restorative care.

La Roche Posay Effaclar H Iso-Biome 40ml

(2,380 reviews)

Moisturizing cream formulated for oily, acne-prone skin that has undergone drying treatments. Restores intense hydration, reduces imperfections, and strengthens the skin barrier for lasting comfort.40 ml packaging. Facial moisturizing cream specifically designed for oily, acne-prone skin weakened by drying treatments. Its formula helps restore lost hydration, alleviating dryness and tightness. It incorporates niacinamide to repair the skin, Orellana extract that acts on excess sebum and hyperkeratinization, and Aqua Posae Filiformis, a key prebiotic to rebalance the skin microbiome. This complex helps reduce the appearance of blemishes, blackheads, and post-acne marks while strengthening the skin's protective function. Its cream texture provides long-lasting hydration without a greasy feel, making it easy to integrate into the daily facial care routine. Suitable for use on the face, especially for skin that experiences dryness after anti-acne treatments, it can be complemented with facial sun protection products and natural makeup for complete protection and a balanced finish. Its soothing and repairing action is compatible with other topical treatments, enhancing the effectiveness of cosmetics adapted for oily skin. Dermatologically tested, this cream helps maintain skin health and improve the overall appearance of imperfect skin through deep, hydrating, and restorative care.

Moisturizing cream formulated for oily, acne-prone skin that has undergone drying treatments. Restores intense hydration, reduces imperfections, and strengthens the skin barrier for lasting comfort.40 ml packaging. Facial moisturizing cream specifically designed for oily, acne-prone skin weakened by drying treatments. Its formula helps restore lost hydration, alleviating dryness and tightness. It incorporates niacinamide to repair the skin, Orellana extract that acts on excess sebum and hyperkeratinization, and Aqua Posae Filiformis, a key prebiotic to rebalance the skin microbiome. This complex helps reduce the appearance of blemishes, blackheads, and post-acne marks while strengthening the skin's protective function. Its cream texture provides long-lasting hydration without a greasy feel, making it easy to integrate into the daily facial care routine. Suitable for use on the face, especially for skin that experiences dryness after anti-acne treatments, it can be complemented with facial sun protection products and natural makeup for complete protection and a balanced finish. Its soothing and repairing action is compatible with other topical treatments, enhancing the effectiveness of cosmetics adapted for oily skin. Dermatologically tested, this cream helps maintain skin health and improve the overall appearance of imperfect skin through deep, hydrating, and restorative care.

$23.37 - $43.00

in 15 offers

The lowest price for La Roche Posay Effaclar H Iso-Biome 40ml right now is $23.37 at drnutrition.com, compared across 15 retailers.

The all-time low was $4.95 on 4 Sept 2026 — today's price is 372% above the lowest ever. It has been notably cheaper before — worth setting a price alert.

Prices last updated 5 Nov 2026.

Price comparison

Price data powered by pricesAPI.io

Last updated at 05/11/2026 23:54:39

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
https://www.google.com/s2/favicons?domain=amazon.com.au&sz=64Amazon.com.au

$26.59

La Roche-Posay Effaclar H Iso-Biome Face Moisturiser For Oily Skin 40ml | For Acne-Prone Sensitive Skin with Damaged Barrier, Repairs & Hydrates

Free delivery

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

https://www.google.com/s2/favicons?domain=drnutrition.com&sz=64drnutrition.com

$23.37

La Roche Posay Effaclar H Iso-biome Moisturizer, 40 ML, Restores Comfort And Hydration.

Delivery between 10–16 Nov $21.61

https://www.google.com/s2/favicons?domain=terrywhitechemmart.com.au&sz=64TerryWhite Chemmart

$23.99

La Roche-Posay Effaclar H Iso-Biome Moisturiser 40ml

Delivery between Sat – Thu $15

https://www.google.com/s2/favicons?domain=chemistwarehouse.com.au&sz=64Chemist Warehouse

$26.59

La Roche Posay Effaclar H Iso Biome Ultra Soothing 40ml

Delivery between Mon – Tue $9.99

https://www.google.com/s2/favicons?domain=chemistdirect.com.au&sz=64Chemist Direct

$29.99

La Roche-Posay Effaclar H Iso-Biome Ultra Soothing Moisturiser 40ml

Delivery by Tue $9.95

https://www.google.com/s2/favicons?domain=frenchbeautyco.com.au&sz=64French Beauty Co

$30.95

Effaclar H Iso-Biome Moisturiser 40ml

Delivery $3

https://www.google.com/s2/favicons?domain=activeskin.com.au&sz=64Activeskin

$31.59

La Roche-Posay Effaclar H Iso-Biome Moisturiser 40ml

Delivery between Mon – Tue $5.95

https://www.google.com/s2/favicons?domain=adorebeauty.com.au&sz=64Adore Beauty

$31.99

La Roche-Posay Effaclar H Biome Moisturiser 40Ml

Delivery between Mon – Wed $7.95

https://www.google.com/s2/favicons?domain=laroche-posay.com.au&sz=64La Roche-Posay Australia Official

$31.99

Effaclar H Isobiome Moisturiser Oily Sensitive Skin | La Roche-Posay

Delivery $9.95

https://www.google.com/s2/favicons?domain=directchemistoutlet.com.au&sz=64Direct Chemist Outlet

$33.99

La Roche-Posay Effaclar H Iso-Biome 40ml

Free delivery between 12–20 Nov

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

A new favourite moisturiser
11 July 2022MaelienyddMae

originally posted on laroche-posay.co.uk

I have been experiencing some painful, but small blemishes and dry areas of skin recently, due to poor health. This left parts of my complexion feeling irritated and sore. I was a little hesitant about trying this moisturiser at first, as it is a little thicker and more emollient than the other effeclar moisturiser. I was concerned it could occlude my skin, causing more white heads. I needn't have worried. This has been a game changer. It spreads well, absorbs easily, and left my skin feeling soothed and hydrated. In combination with the effaclar cream cleanser, i noticed a vast reduction in breakout within a week. This boosted my confidence, as i was feeling self-conscious about the acne breakout. It works well with my Anthelios sun cream, without pilling. A new ... MoreI have been experiencing some painful, but small blemishes and dry areas of skin recently, due to poor health. This left parts of my complexion feeling irritated and sore. I was a little hesitant about trying this moisturiser at first, as it is a little thicker and more emollient than the other effeclar moisturiser. I was concerned it could occlude my skin, causing more white heads. I needn't have worried. This has been a game changer. It spreads well, absorbs easily, and left my skin feeling soothed and hydrated. In combination with the effaclar cream cleanser, i noticed a vast reduction in breakout within a week. This boosted my confidence, as i was feeling self-conscious about the acne breakout. It works well with my Anthelios sun cream, without pilling. A new favourite

Fantastic for sensitive blemished skin
20 June 2022MumUK

originally posted on laroche-posay.co.uk

I recently started adding Effaclar H Moisturiser into my evening routine as my skin was looking increasingly red & sensitive, particularly on my cheeks. I’m so glad I’ve discovered this product, it’s making a significant difference within just a couple of days & my skin feels like silk when I wake up (rather than red & thight which it was before). It’s so good to discover a product that works so well for sensitive blemished skin. I love how it soothes and calms my skin & you can see how quickly it gets to work strengthening the skin barrier so it feels & looks healthier. It’s definitely doing what I wanted it to do, reducing redness & helping to minimise my blemishes & blackheads.

Great product
17 November 2022Ray R.

originally posted on beautycrew.com.au

I love la Roche-pissu products . I use a few products from their range. I recently purchased this La Roche-Posay Effaclar H Iso-Biome Moisturiser and I love it so much. It’s made a huge difference to my face. I have sensitive skin at times and I was looking for a good cream after my skin flared up cz of a cream. I felt this will help calm down my skin. And it did just that. I love how soft it made my skin. It calmed down the skin flare and hydrated my skin well without making it oily. Highly recommend this La Roche-Posay Effaclar H Iso-Biome Moisturiser

Specification

BenefitSoothing, Hydrating
Body PartFace
FormCream
Skin TypeOily skin
Active IngredientsNiacinamide

Price comparison

Updated 1 day ago
Please note: price history and price alerts are not available for some stores, including Amazon.com.au.
https://www.google.com/s2/favicons?domain=amazon.com.au&sz=64
Amazon.com.au

$26.59

La Roche-Posay Effaclar H Iso-Biome Face Moisturiser For Oily Skin 40ml | For Acne-Prone Sensitive Skin with Damaged Barrier, Repairs & Hydrates

Free delivery

Affiliate Disclosure: We may receive a small commission for purchases made through this link at no extra cost to you. This helps support our site. Thank you!

https://www.google.com/s2/favicons?domain=drnutrition.com&sz=64
drnutrition.com

$23.37

La Roche Posay Effaclar H Iso-biome Moisturizer, 40 ML, Restores Comfort And Hydration.

Delivery between 10–16 Nov $21.61

https://www.google.com/s2/favicons?domain=terrywhitechemmart.com.au&sz=64
TerryWhite Chemmart

$23.99

La Roche-Posay Effaclar H Iso-Biome Moisturiser 40ml

Delivery between Sat – Thu $15

https://www.google.com/s2/favicons?domain=chemistwarehouse.com.au&sz=64
Chemist Warehouse

$26.59

La Roche Posay Effaclar H Iso Biome Ultra Soothing 40ml

Delivery between Mon – Tue $9.99

https://www.google.com/s2/favicons?domain=chemistdirect.com.au&sz=64
Chemist Direct

$29.99

La Roche-Posay Effaclar H Iso-Biome Ultra Soothing Moisturiser 40ml

Delivery by Tue $9.95

Price history

Price history

Please note: price history and price alerts are not available for some stores, including Amazon.com.au.

Reviews

A new favourite moisturiser
11 July 2022

I have been experiencing some painful, but small blemishes and dry areas of skin recently, due to poor health. This left parts of my complexion feeling irritated and sore. I was a little hesitant about trying this moisturiser at first, as it is a little thicker and more emollient than the other effeclar moisturiser. I was concerned it could occlude my skin, causing more white heads. I needn't have worried. This has been a game changer. It spreads well, absorbs easily, and left my skin feeling soothed and hydrated. In combination with the effaclar cream cleanser, i noticed a vast reduction in breakout within a week. This boosted my confidence, as i was feeling self-conscious about the acne breakout. It works well with my Anthelios sun cream, without pilling. A new ... MoreI have been experiencing some painful, but small blemishes and dry areas of skin recently, due to poor health. This left parts of my complexion feeling irritated and sore. I was a little hesitant about trying this moisturiser at first, as it is a little thicker and more emollient than the other effeclar moisturiser. I was concerned it could occlude my skin, causing more white heads. I needn't have worried. This has been a game changer. It spreads well, absorbs easily, and left my skin feeling soothed and hydrated. In combination with the effaclar cream cleanser, i noticed a vast reduction in breakout within a week. This boosted my confidence, as i was feeling self-conscious about the acne breakout. It works well with my Anthelios sun cream, without pilling. A new favourite

MaelienyddMae originally posted on laroche-posay.co.uk
Fantastic for sensitive blemished skin
20 June 2022

I recently started adding Effaclar H Moisturiser into my evening routine as my skin was looking increasingly red & sensitive, particularly on my cheeks. I’m so glad I’ve discovered this product, it’s making a significant difference within just a couple of days & my skin feels like silk when I wake up (rather than red & thight which it was before). It’s so good to discover a product that works so well for sensitive blemished skin. I love how it soothes and calms my skin & you can see how quickly it gets to work strengthening the skin barrier so it feels & looks healthier. It’s definitely doing what I wanted it to do, reducing redness & helping to minimise my blemishes & blackheads.

MumUK originally posted on laroche-posay.co.uk
Great product
17 November 2022

I love la Roche-pissu products . I use a few products from their range. I recently purchased this La Roche-Posay Effaclar H Iso-Biome Moisturiser and I love it so much. It’s made a huge difference to my face. I have sensitive skin at times and I was looking for a good cream after my skin flared up cz of a cream. I felt this will help calm down my skin. And it did just that. I love how soft it made my skin. It calmed down the skin flare and hydrated my skin well without making it oily. Highly recommend this La Roche-Posay Effaclar H Iso-Biome Moisturiser

Ray R. originally posted on beautycrew.com.au
Have I found a holy grail?
7 November 2022

I never knew the old formula, and I bought this product two weeks ago for the first time. I am 37, I have a sensitive oily blemish-prone skin, dehydrated by many anti-acne products (retinols and acids). For many years, everyone told me that my skin barrier is broken and I need a good moisturizer. I tried many, but always had bad reactions, and only three things were able to calm my skin, more or less: aloe gel, snail mucin (pure) and a very expensive barrier repair cream from Dermalogica. And then, just by chance, I bought this one. At first, I was impressed how this cream was able to reduce dehydration-related redness. Then, I was impressed by how make-up products looked on top of it. But then, there was a revelation: I ate some chocolate - and my skin didn't break ... MoreI never knew the old formula, and I bought this product two weeks ago for the first time. I am 37, I have a sensitive oily blemish-prone skin, dehydrated by many anti-acne products (retinols and acids). For many years, everyone told me that my skin barrier is broken and I need a good moisturizer. I tried many, but always had bad reactions, and only three things were able to calm my skin, more or less: aloe gel, snail mucin (pure) and a very expensive barrier repair cream from Dermalogica. And then, just by chance, I bought this one. At first, I was impressed how this cream was able to reduce dehydration-related redness. Then, I was impressed by how make-up products looked on top of it. But then, there was a revelation: I ate some chocolate - and my skin didn't break out! That's utterly fantastic! So, I don't know about the difference between the old formula and the new formula, but at the moment it works for me brilliantly, and I am now a devoted fan. Thank you for this product

Teav originally posted on laroche-posay.co.uk
Hydrating feel.
6 July 2022

I have rosacea therefore initially when I received this product I was concerned in case it would make my skin flare up. AIso I don’t use any products that cause over drying so wasn’t sure if this product was right for my skin type. My skin is very sensitive so the wrong products for my skin would make my blemishes a lot worse and my skin to go very red. However I have been very pleasantly surprised with this product. I have been using the moisturiser every day for over a week and find it very hydrating. I don’t need to use much at all either. It leaves my skin looking like it’s been moisturised. But above all it hasn’t caused my sensitive skin to flare up at all. So I am extremely pleased. Additionally I have a few patches of dry skin and they disappear with this ... MoreI have rosacea therefore initially when I received this product I was concerned in case it would make my skin flare up. AIso I don’t use any products that cause over drying so wasn’t sure if this product was right for my skin type. My skin is very sensitive so the wrong products for my skin would make my blemishes a lot worse and my skin to go very red. However I have been very pleasantly surprised with this product. I have been using the moisturiser every day for over a week and find it very hydrating. I don’t need to use much at all either. It leaves my skin looking like it’s been moisturised. But above all it hasn’t caused my sensitive skin to flare up at all. So I am extremely pleased. Additionally I have a few patches of dry skin and they disappear with this moisturiser. It’s a gentle moisturiser which is what I need, doesn’t aggravate my sensitive skin and leaves it looking moisturised. Nor do I need to put much on to achieve this outcome. I am going to keep using this moisturiser. In my opinion I feel that this moisturiser is suitable for rosacea prone skin also.

originally posted on laroche-posay.co.uk
Light and easy to spread moisturiser
29 June 2022

It has onky been a week since ive started using this cream and i have to say, that so far and by far it is my favourite product sent by La Roche. For the past 3 weeks I have been going through bereavement after suddenly loosing my fiance. I have not been paying attention to my skin needs, and over the last 3 weeks it became dull, dry, flacky, very unhealthy looking. This cream is slowly changing it. With oily and fairly sensitive skin it is providing me with required hydration. It has a rich comforting feeling yet is doesn't make it looking oilier. No offensive smell or formula.

Karolina Cz originally posted on laroche-posay.co.uk
New & unimproved.From holy grail to my daily fail!
7 November 2022

I have been using effaclar H moisturiser for several years and recommended it to family and friends. In combination with LRP cleanser, it completely changed my skin from dry, irritated, acne break outs to clear, glowing, healthy and moisturised. However, the formula changed a few months ago and after application it now feels like a film sitting on my face. The moisturiser pills, I’m experiencing a lot of break outs, and my skin is visibly dry. Very upset that the formula has been changed and I am now on the search for a new moisturiser as I won’t be buying the new and unimproved effaclar H again.

Samanth originally posted on laroche-posay.co.uk
Please bring back the original formula Effaclaie H
19 December 2022

I have loved effaclair H since I was first recommended it, and have been using it for over 10 years. I recently stocked back up with 3 tubes as I usually do when I'm running out. At first I thought maybe I ordered the wrong product and it had a fragrance to it and I noticed it wasn't moisturising my skin like before. I checked my order and saw a review mentioning the same as me, a new but worse formula. Please bring back the original. It's far better. I'm so disappointed as always felt paying more for this cream was so worth it. Now I'm stuck with 3 tubes of moisturiser that isn't a patch on the old version. Sad sad sad :(

SarahG originally posted on laroche-posay.co.uk
The perfect face moisturizer
13 December 2022

This lotion along with the face wash has almost transformed my problem area, T-zone into a something manageable that I do not think I have had in really long time. It is really helping me recover my skin barrier. please do not stop making this!. It feels so good to know that those little plugs on my nose were becoming oxidized and brown and had to be picked out because something was not right with my skin barrier. It is the best feeling in world to be able to wash face, put lotion on and not have to worry about crap sticking out of your pores. This is really changing my skin and I love it. I will say I also use benzoyl peroxide which I had never dared to use on my T-zone and I am sure that is helping as well but I am only able to do that because the face wash is ... MoreThis lotion along with the face wash has almost transformed my problem area, T-zone into a something manageable that I do not think I have had in really long time. It is really helping me recover my skin barrier. please do not stop making this!. It feels so good to know that those little plugs on my nose were becoming oxidized and brown and had to be picked out because something was not right with my skin barrier. It is the best feeling in world to be able to wash face, put lotion on and not have to worry about crap sticking out of your pores. This is really changing my skin and I love it. I will say I also use benzoyl peroxide which I had never dared to use on my T-zone and I am sure that is helping as well but I am only able to do that because the face wash is gentle enough and the cream is hydrating enough. All I know is that I get a full day of less oily skin. Please do not stop making this and bring this to the USA if possible. I have to buy expensive from over seas :(..hope there is someone out there listening.

hello8 originally posted on laroche-posay.co.uk
Very good. Great summer moisturiser for normal skin. Also good for acne skin.
29 June 2022

This is a great moisturiser. I get breakouts in the summer months. Not really any other time. I switch to this for a couple of months and it sorts my skin out (along with the cleanser in the range), then I go back to more hydrating/thicker products for autumn and winter. My nephew has acne skin and he has used it. It calms his flare ups but isn’t a miracle worker. It counteracts the drying effects of other acne products.

Mitsyfry originally posted on laroche-posay.co.uk

Specification

BenefitSoothing, Hydrating
Body PartFace
FormCream
Skin TypeOily skin
Active IngredientsNiacinamide

You may also like

La Roche Posay Effaclar H Iso Biome Soothing and Hydrating Moisturiser
La Roche Posay Effaclar H Iso Biome Soothing and Hydrating Moisturiser$17.98 - $46.99
Compare 19 offers
- 12%
La Roche Posay Effaclar H Iso-Biome Cleansing Cream 200 ml
La Roche Posay Effaclar H Iso-Biome Cleansing Cream 200 ml$5.55 - $65.00
★★★★★★★★★★
2,106
Compare 55 offers
- 17%
La Roche Posay Effaclar Duo (+) 40ml
La Roche Posay Effaclar Duo (+) 40ml$25.97 - $194.73
★★★★★★★★★★
5,114
Compare 34 offers
- 4%
La Roche-Posay Effaclar Supramolecular 40ml
La Roche-Posay Effaclar Supramolecular 40ml$17.06 - $41.99
Compare 14 offers
- 5%
La Roche-Posay Effaclar Duo Unifiant 40ml
La Roche-Posay Effaclar Duo Unifiant 40ml$25.37 - $70.00
★★★★★★★★★★
2,615
Compare 51 offers
La Roche-Posay Effaclar Duo Unifiant 40ml
La Roche-Posay Effaclar Duo Unifiant 40ml$22.18 - $109.69
★★★★★★★★★★
1,714
Compare 53 offers