Overview Advocate for Dogs Over 25 kg is an easy to use, water resistant monthly spot-on that provides comprehensive protection from fleas, heartworm disease, intestinal worms, oesophageal worm, mites and lice. Advocate is a fast-acting, water resistant, easy to apply monthly spot-on offering comprehensive parasite protection. It kills fleas fast and on contact, so there's no need for them to bite! Reinfesting fleas stop biting in 3-5 minutes and are killed within 1 hour. Larval flea stages are killed in the dog's surroundings, and it reduces the incidence of flea allergy dermatitis. Also treats and controls lice as well as mange and ear mites. Advocate prevents heartworm disease and treats and controls adult & juvenile stages of roundworms and hookworms. Advocate is unique, providing ongoing protection from new worm infestations between treatments, meaning less egg shedding and risk of disease. It also kills whipworm and aids in the prevention of flea tapeworm. Advocate is the only product that protects against the deadly oesophageal worm. Safe for use on puppies from 7 weeks of age and any weight.